How much do Western versions of the Bible, e.g., the New Revised Standard Version, differ from prominent Orthodox translations?

The writers and interpreters of modern western translations of the Holy Bible tend to use the Hebrew translations of the Old Testament, and the Greek translations of the New Testament as focal points for translation. The New Revised Standard Version (NRSV) of the Bible makes a point of being “as literal as possible” when translating from Hebrew and Greek to modern-day English.

In contrast, the writers and interpreters of prominent Orthodox translations of the Holy Bible tend to translate from the “Septuagint,” which is the Greek Old Testament; the Greek New Testament is used as well by the translators of the Orthodox versions of the Bible, making the entire translation from the Greek language.

Another key difference between these translations is their differences in literary variety. The Greek/Eastern Orthodox Bibles use Masoretic elements in their texts in addition to their Greek translations. Masoretic Bibles have Rabbinical footnotes and are Talmudic in nature, meaning that they are edited and so forth to the aid of Jewish Rabbis.

The NRSV on the other hand, is available in three formats: a standard edition with or without the Apocrypha, a Roman Catholic Edition, which has the "Apocryphal" or "Deutero-canonical" books in the Roman Catholic canonical order, and The Common Bible, which includes all books that belong to the Protestant, Roman Catholic, and Orthodox canons.